Structure and Mechanism of DNA Repair Enzymes

DNA repair enzymes are enzymes that recognize and correct physical damage in DNA, caused by exposure to radiation, UV light or reactive oxygen species. DNA Damage Repair Enzymes are necessary for the repair of errors introduced during DNA replication or recombination or as a result of treatment with exogenous genotoxic agents. These enzymes can be used in vitro to detect specific forms of DNA damage or for repair assays. Importantly, our understanding of the fundamental science behind DNA repair and the mechanisms of the enzymes involved has led to a number of therapeutic strategies to treat these diseases. This book provides selected topics in DNA repair, a field that is ever-expanding in complexity and biologic significance. 

Print ISBN: 9781682516836| $ 155 | 2020 | Hardcover

Contributors: K. Y. Huang